End point

An end point, in the context of a clinical trial, refers to an outcome experienced by the participants of the trial that evidences the impact of the medicine or treatment being trialed, typically pre-agreed upon by the FDA and the entity running the trial. An end point can take the form of a desired clinical outcome (e.g., a reduction in blood pressure in a trial for pressure-reduction pills) or something that offers indirect evidence of a desired clinical outcome, known as a surrogate end point.